• Autor: Mary Miu Yee Waye
  • Editor: Nova Science Publishers Inc
  • Last data published: 01 May 2015
  • ISBN: 1634823125
  • Format: PDF, Epub, DOCx, TXT
  • Number of page: 151 pages
  • File Size: 32MB
  • Rating:


Advertising


Description Biochemistry and Molecular Biology de Mary Miu Yee Waye:

Even though the ApoA5 gene was discovered over 13 years ago by Pennacchio et al, 2001 [1], and it was known then the gene influences triglycerides, leading to speculations that it would affect the risk of stroke- the factors that affect cardiovascular diseases are very complex. Larry Baum's group shown that APOA5 genotypes were not significantly associated with strokes or stroke subtypes in the cohort they studied [2]. The discovery of the ApoA5 gene was very special in that, unlike many other genes discovered through studying a known protein or enzyme, advanced bioinformatics was used for the initial gene discovery, an amazing feat that could not have been done without knowledge of the human genome. The laborious effort in deciphering the genome was very controversial in its infancy, and voices of opposition nearly led to premature abortion of the project, and much of the objection was voiced due to the doubt of spending a huge budget in sequencing what was thought to be useless (ie: for a major proportion (98%) of "junk DNA" at that time). However, recently it was shown that deleting a non-coding region of what was thought to be "junk DNA" could lead to narrowing of arteries in mice [3] so that might offer an explanation that there are more to the story of stroke risk factors than merely studying APOA5, and such findings just remind us time and again, often the basic research could laid the foundation that is very essential for discoveries made by clinicians or the translational/applied scientists. Mary Miu Yee Waye is a Professor at the School of Biomedical Sciences, President, Hong Kong Society of Biochemistry and Molecular Biology, Founding Director, Croucher Laboratory for Human Genomics, The Chinese University of Hong Kong, Hong Kong

Download Free Biochemistry and Molecular Biology :

Biochemistry and Molecular Biology MP3Biochemistry and Molecular Biology Mp3
Biochemistry and Molecular Biology PDFBiochemistry and Molecular Biology PDF
Biochemistry and Molecular Biology EPUBBiochemistry and Molecular Biology EPUB
Biochemistry and Molecular Biology TXTBiochemistry and Molecular Biology TXT
Biochemistry and Molecular Biology DOCBiochemistry and Molecular Biology DOC
Biochemistry and Molecular Biology MOBIBiochemistry and Molecular Biology MOBI

Comments

Leyton Re: Biochemistry and Molecular Biology

Surprise! In fact, I like it.

Asley Re: Biochemistry and Molecular Biology

I'm glad I finally downloaded the epub versions. I am very happy.

Bladeshaper Re: Biochemistry and Molecular Biology

I'm glad I finally downloaded the epub versions. I am very happy.

Leonel Re: Biochemistry and Molecular Biology

I started reading this book and I'm in one of its 123 pages.

Nuadaghma Re: Biochemistry and Molecular Biology

Let me be relevant for a moment: My God, this book is outstanding !!

Leave a Comment